By OkayGoal 
It’s a massive weekend in Spain, with El Clasico taking place at the Bernabeu on Sunday. Real Madrid hold a two-point advantage on Barcelona heading into the match. Elsewhere, there’s a key game at the bottom between Girona and Real Oviedo, while Betis host Atletico Madrid on Monday.
Here are our LaLiga predicted lineups for matchday 10. All kick-off times are based on the local time in Spain. Players in bold are those considered to have the highest chance of starting (80% or more).
LaLiga predicted lineups – Matchday 10
Friday 24th October 2025
21:00 – Real Sociedad vs Sevilla
Real Sociedad predicted lineup
Remiro – Gomez, Caleta-Car, Zubeldia, Aramburu – Soler, Gorrotxategi, Herrera – Barrenetxea, Oyarzabal, Guedes (4-3-3)
Sevilla predicted lineup
Vlachodimos – Suazo, Marcao, Cardoso, Carmona – Gudelj, Agoume – Vargas, Sow, Juanlu – Adams (4-2-3-1)
Saturday 25th October 2025
14:00 – Girona vs Real Oviedo
Girona predicted lineup
Gazzaniga – Moreno, Blind, Reis, A. Martinez – Martin, Witsel – Roca, Portu, Gil – Vanat (4-2-3-1)
Real Oviedo predicted lineup
Escandell – Alhassane, Carmo, Bailly, Vidal – Colombatto, Dendoncker – Chaira, Reina, Hassan – Viñas (4-2-3-1)
16:15 – Espanyol vs Elche
Espanyol predicted lineup
Dmitrovic – Romero, Riedel, Calero, El Hilali – Milla, Exposito, Lozano, Dolan – R. Fernandez, K. Garcia (4-4-2)
Elche predicted lineup
Peña – Bigas, Affengruber, Chust – Valera, Neto, Febas, Aguado, Nuñez – A. Silva, Mir (3-5-2)
18:30 – Athletic Club vs Getafe
Athletic Club predicted lineup
Simon – Boiro, Paredes, Vivian, Areso – Jauregizar, Ruiz de Galarreta – N. Williams, Sancet, Navarro – Guruzeta (4-2-3-1)
Getafe predicted lineup
Soria – Rico, Djene, Duarte, Iglesias, Femenia – Arambarri, Milla, Martin – Mayoral, Liso (5-3-2)
21:00 – Valencia vs Villarreal
Valencia predicted lineup
Agirrezabala – Gaya, Comert, Tarrega, Correia – D. Lopez, Santamaria, Guerra, Rioja – Danjuma, Duro (4-4-2)
Villarreal predicted lineup
Tenas – Cardona, Marin, Veiga, Mouriño – Moleiro, Parejo, Gueye, Akhomach – Ayoze, Oluwaseyi (4-4-2)
Sunday 26th October 2025
14:00 – Mallorca vs Levante
Mallorca predicted lineup
Roman – Mojica, Valjent, Raillo, Maffeo – Morlanes, S. Costa – Virgili, Darder, Joseph – Muriqi (4-2-3-1)
Levante predicted lineup
Ryan – M. Sanchez, Moreno, De la Fuente, Toljan – Brugui, Rey, Arriaga, P. Martinez – Romero, Etta Eyong (4-4-2)
16:15 – Real Madrid vs Barcelona
Real Madrid predicted lineup
Courtois – Carreras, Huijsen, Militao, Valverde – Bellingham, Tchouameni, Guler – Vinicius, Mbappe, Mastantuono (4-3-3)
Barcelona predicted lineup
Szczesny – Balde, E. Garcia, Cubarsi, Kounde – Pedri, De Jong – Rashford, Fermin, Yamal – Ferran (4-2-3-1)
18:30 – Osasuna vs Celta Vigo
Osasuna predicted lineup
Herrera – Catena, Herrando, Boyomo – Bretones, Moncayola, Torro, Benito – Ruben Garcia, Muñoz – Budimir (3-4-2-1)
Celta Vigo predicted lineup
Radu – Alonso, Dominguez, J. Rodriguez – Mingueza, Moriba, Sotelo, Rueda – Jutgla, Duran – Iglesias (3-4-2-1)
21:00 – Rayo Vallecano vs Alaves
Rayo Vallecano predicted lineup
Batalla – Chavarria, Mendy, Lejeune, Ratiu – Valentin, U. Lopez – F. Perez, Isi, De Frutos – Alemão (4-2-3-1)
Alaves predicted lineup
Sivera – Youssef, Pacheco, Tenaglia, Jonny – Rebbach, Blanco, Ibañez, Calebe – T. Martinez, Boye (4-4-2)
Monday 27th October 2025
21:00 – Real Betis vs Atletico Madrid
Real Betis predicted lineup
Lopez – Firpo, Natan, Bartra, Bellerin – Amrabat, Fornals – Abde, Lo Celso, Antony – C. Hernandez (4-2-3-1)
Atletico Madrid predicted lineup
Oblak – Hancko, Gimenez, Le Normand, Llorente – Gonzalez, Koke, Barrios, Simeone – Baena – Alvarez (4-4-1-1)
Mark is a freelance football writer based in Madrid, and the editor of LaLigaExpert.com. He has been covering LaLiga and European football since 2014.